Pyruvate dehydrogenase from Azotobacter vinelandii

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Succinic dehydrogenase of Azotobacter vinelandii.

During the investigation of the Krebs cycle in Azotobacter agile, strain 4.4 (Repaske and Wilson, 1953), it was found that whole cells normally required 20 minutes before adaptation to succinate, but succinoxidase activity could be demonstrated in cell-free extracts made from unadapted cells. If extracts prepared in a 10 kc Raytheon sonic oscillator were centrifuged at 145,000 G for 30 minutes,...

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Pyruvate dehydrogenase from Azotobacter vinelandii. Properties of the N-terminally truncated enzyme.

The pyruvate dehydrogenase multienzyme complex (PDHC) catalyses the oxidative decarboxylation of pyruvate and the subsequent acetylation of coenzyme A to acetyl-CoA. Previously, limited proteolysis experiments indicated that the N-terminal region of the homodimeric pyruvate dehydrogenase (E1p) from Azotobacter vinelandii could be involved in the binding of E1p to the core protein (E2p) [Hengeve...

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The reduction of flavodoxin from Azotobacter vinelandii by pyruvate.

The flavoprotein from Azotobacter, first isolated by SHETHNA et al. 1, is chemically well characterized, but its enzymatic function is still obscure. ARNON and coworkers 2 found this flavoprotein to be active in substituting for ferredoxin in the reduction of acetylene by a cell-free nitrogenase preparation from Azotobacter. We have recently confirmed their observation3. In addition, we could d...

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Genes in Azotobacter vinelandii

Azotobacter vinelandii contains a heterodimeric, membrane-bound [NiFelhydrogenase capable of catalyzing the reversible oxidation of H2. The 13 and at subunits of the enzyme are encoded by the structural genes hoxK and hoxG, respectively, which appear to form part of an operon that contains at least one further potential gene (open reading frame 3 1ORF3]). In this study, determination of the nuc...

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Cytochrome c oxidase from Azotobacter vinelandii.

Although the terminal respiratory chain of Azotobacter has been the subject of several recent studies, the nature of the cytochrome oxidase portion is still somewhat obscure. Repaske (1) partially purified and characterized a soluble succinic dehydrogenase and succinoxidase system from Azotobacter z&elan&i. Wilson and Wilson (2) studied the soluble succinoxidase in Repaske’s preparation and dem...

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ژورنال

عنوان ژورنال: European Journal of Biochemistry

سال: 2001

ISSN: 0014-2956,1432-1033

DOI: 10.1046/j.1432-1327.1999.00852.x